// Principal investigator
Paul Bourgine
Paul Bourgine is Associate Professor of Molecular Skeletal Biology at Lund University and Principal Investigator of the Laboratory for Bone Organ Modeling and Regeneration. He trained in biotechnology at the École Supérieure de Biotechnologie de Strasbourg. He established the Bourgine Lab at Lund University in 2018.
His research focuses on bone as an integrated organ system, from the molecular identity and function of BM-MSCs to the engineering of human tissue models and translatable regenerative strategies. Since founding the lab, he has secured prestigious national and international grants, including VR, ERC Starting and Consolidator grants, and an EIC consortium grant. Paul also co-founded Dhalion Biotech AB, the lab's spin-off company.
Paul is a WCMM Fellow and a member of the Lund Stem Cell Center, the Lund University Cancer Centre, and the StemTherapy national initiative.
// The team
The people behind the research
The Bourgine Lab brings together researchers from across Europe and beyond, united by a shared interest in bone organ biology and a commitment to human-specific experimental approaches.
PhD student
David Hidalgo Gil
Master in Bioinformatics, Lund University
Deciphering the molecular mechanisms of bone formation and repair
Research assistant
Alex Antill
Master of Medical Science, Lund University
Haematopoietic stem cells and their involvement in disease
Postdoctoral researcher
Camille Sauter
PhD in Cellular and Molecular Biology, University of Dijon
Building and exploiting patient-specific models of Acute Myeloid Leukemia
Postdoctoral researcher
Alejandro Garcia Garcia
PhD in Bioengineering and Biomaterials, Universite de Technologie de Compiegne
Bone tissue engineering and regeneration
Master student
Patricia Ramos
Bachelor in Biochemistry, University of Seville
Role of the tumor microenvironment in immune evasion and therapy resistance
PhD student
Laura Rabanal Cajal
Master in Genetics, Universite Paris Cite
Bone marrow immunoregulation and its implications for dendritic cell immunotherapies in leukemia
Postdoctoral researcher
Aurelie Baudet
PhD in Cellular and Molecular Biology, University of Montpellier
Leukemia and bone marrow niche remodeling
Postdoctoral researcher
Sara Gonzalez Anton
PhD, Imperial College London
Bone marrow niche role in cancer development and cancer therapy response
Master student
Chiara Colombo
Bachelor in Medical Biotechnology, Universita del Piemonte Orientale
Spatial and immune cell interactions within the tumor microenvironment
ALUMNI
Elia Pennati, Leen Fadlallah, Sacha Bosch, Sara Savino, Sujeethkumar Prithiviraj, Ani Grigoryan, Alexandra Chatzidaniil, Bai Yiguang, Sonia Ferveur, Joao Pinheiro, Karin Linderfalk, Pilar Lorenzo, Lucille Degos, Ludovica Perotti, Medea Gabriel, Melissa Langlois, Nasim Kalantari, Panajot Kristofori, Steven Dupard, Suvi Vallius, Tommi Glorioso, Yuan Liu.
// Affiliated research centres
Embedded within Lund University's Faculty of Medicine and four research centres
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Paul Bourgine is a WCMM Fellow. The Centre supports investigator-led molecular medicine research at Lund University.
One of Sweden's principal stem cell research nodes. The lab's work on mesenchymal and haematopoietic stem cell biology is integrated into the Center's collaborative programmes.
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The LUCC connects oncology research across Lund University. The lab contributes through its work on bone marrow niche biology and haematological malignancies.
A Swedish national research initiative on stem cell-based therapies, in which the lab participates as a member group.
// FUNDING & GRANTS
Over six million euros in competitive funding since 2018. Our research is supported by national and international programmes that recognise the scientific and translational potential of bone organ biology.
ERC Starting, Consolidator and Proof-of-concept grants, development of humanised ossicle models and the OssiGel bone matrix technology.
Starting Grant supporting the lab's fundamental programme in skeletal stem cell biology.
Funding supporting the lab's research on bone marrow niche biology and its relevance to metabolic and haematological disease contexts.
Funding channelled through the WCMM framework, supporting the molecular medicine research programme.
Funding for haematological malignancy research and bone marrow microenvironment studies.
Funding supporting translation of bone engineering technologies, including through Dhalion Biotech AB.
Our alumni
Postdoctoral researcher
Dimitra Zacharaki
Wallenberg Centre for Molecular Medicine - Lund
Postdoctoral researcher
Alejandro Garcia-Garcia
Wallenberg Centre for Molecular Medicine - Lund
PhD student
David Hidalgo Gil
Wallenberg Centre for Molecular Medicine - Lund
Researcher
Aurelie Baudet
Lund University
Postdoctoral Researcher
Sara González Antón
Lund University
Postdoctoral Researcher
Camille Sauter
Lund University, Lund
PhD student
Laura Rabanal Cajal
Lund University
Master's student
Chiara Colombo
Università degli Studi di Milano Statale, Milan
Visiting PhD student
Elia Pennati
Politecnico di Milano, Milan
// Join us
Open to new collaborators and applicants
We are always looking for motivated researchers at the Master, PhD, and postdoctoral level — with backgrounds in molecular biology, immunology, developmental biology, bioinformatics, or tissue engineering.
You are welcome in a collaborative, international environment where fundamental and translational science go hand in hand.