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2023
Sustained delivery of a heterodimer bone morphogenetic protein-2/7 via a collagen hydroxyapatite scaffold accelerates and improves critical femoral defect healing
Acta Biomaterialia
10.1016/j.actbio.2023
Liu Y, Puthia M, Sheehy EJ, Ambite I, Petrlova J, Prithviraj S, Oxborg MW, Sebastian S, Vater C, Zwingenberger S, Struglics A, Bourgine PE, O'Brien FJ, Raina DB
An ultra-low dose (0.5 μg) of BMP-2/7 accelerated fracture healing and performed at a level comparable to 20-times higher BMP-2 dose.
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