Bone as an Organ system

Bone is a complex Organ offering structural and mechanical support of our body, but also consisting in our principal hematopoietic center. The formation of Bone involves distinct stages, including cartilage, vasculature, bone and bone marrow establishment. Our lab aims at compiling human-specific knowledge on these processes, toward the development of innovative Regenerative Therapies.

Study of processes involved in Bone formation for design of regenerative therapies

AIM 1: in vivo models

Deciphering the cellular/molecular
mechanisms involved in Bone formation

AIM 2: in vitro models

In vitro development
of 3D Bone models

AIM 3: Design of 3D grafts

Design of customized
3D grafts for skeletal tissue regeneration