Wanna collaborate with us?

 

We are always interested by highly motivated young scientists at the Master, PhD and Post-doctoral level! Applicants with an international research experience and strong background in molecular biology/immunology/developmental biology/bioengineering are encouraged to apply. You will be most welcome in a young, friendly and dynamic environment. See below positions detailed. Please provide your CV, motivation statement and up to 3 referees at: paul.bourgine@med.lu.se

GENERAL INFORMATION

 

The lab: The successful candidates will be part of the novel laboratory for Cell, Tissue and Organ engineering. The laboratory is part of the Wallenberg Centre for Molecular Medicine (WCMM LU), at the Lund Faculty of Medicine (https://www.med.lu.se/english). Focusing on regenerative medicine (regeneration, replacement and repair), WCMM LU is part of a national effort to strengthen Sweden as a world-leading life science nation (https://www.med.lu.se/wcmm).

Our lab aims at deciphering the cellular & molecular mechanisms occurring during phases of bone formation/repair. Using state-of-the-art 3D culture systems, death-inducible human mesenchymal lines and tissue engineering protocols, we focus on studying processes of cartilage/bone/bone marrow establishment in human(ized) contexts. Compiled knowledge will be used for the design of cell-based but cell-free extracellular matrices, to be used as smart-materials for skeletal repair. As such, the lab covers both fundamental and translation research aspects. More information available on our website: www.bourginelab.com

 

The University: The lab located within the BioMedical Center at the Faculty of Medicine, and is part of Lund University (Sweden). The university was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. Lund University has 42 000 students and 7 400 staff based in Lund, Helsingborg and MalmöThe Faculty of Medicine as part of Lund University is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world. Easily accessible via Copenhagen airport (35min), Lund is a dynamic and well-connected city in the heart of the Scandinavian hub.

 

OPEN POSITIONS

Master students:

Young scientists with a bioengineering or biological background are welcome to apply for internships. Backgounds in molecular biology, transcriptomics/proteomics data analysis, 3D printing, cell culture techniques are particularly appreciated. Projects are typically designed taking into account both the candidate interest and the need of the laboratory.

 

Post-doctoral position (position #001):

Work assignments: The candidate will exploit novel human death-inducible cell lines for the generation of biological extracellular matrices customized in composition. Those cell-based but cell-free grafts will be characterized and validated in various animal models of bone repair. The candidate will target the GMP and scaled-up production of such materials, toward its pre-clinical validation. The candidate is also expected to decode the cellular/molecular events driving bone formation in this model. The project combined both key translational and fundamental features.

Ideal profile: You are a freshly graduated PhD looking for a post-doctoral experience to complement your existing skills/background. You have experience in tissue engineering, and ideally knowledge on bone development, biology and regeneration. You are familiar with cell culture techniques, flow cytometry, and handlings of animals. The laboratory will offer you robust training in human cellular biology, engineering of human cells/tissues/organs, as well as in manipulation of 3D culture systems. Desirable skills include an excellent speaking/writing English levels. Experience in molecular biology, 3D culture, confocal microscopy or analysis of sequencing data is a plus.

Qualifications: Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the last date for applications. Under special circumstances, the doctoral degree can have been completed earlier.

 

PhD or Post-doctoral (position #002):

Work assignments: The candidate will design and validate novel 3D bioreactor systems for the production of skeletal grafts. A 3D-printing technology will be exploited for the rapid generation of bioreactors presenting custom shape and dimension. Combining the new devices with our cell lines will allow the engineering of complex tissue for bone repair.

Ideal profile: You are a freshly graduated PhD looking for a post-doctoral experience to complement your existing skills/background. You are familiar with the use of 3D printing technologies, from the design to the production. An experience in tissue engineering is a plus, as well as knowledge on bone or cartilage tissues. You are familiar with cell culture techniques, flow cytometry, and capable of handlings of animals. The laboratory will offer you robust training in human cellular biology, engineering of human cells/tissues/organs, as well as in manipulation of 3D culture systems. Desirable skills include an excellent speaking/writing English levels. Experience in molecular biology, 3D culture, confocal microscopy or sequencing data is a plus.

Qualifications: Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the last date for applications. Under special circumstances, the doctoral degree can have been completed earlier.