Closing the 2023 LU SCC conference

This week the CTO team joined the 2023 Lund Stem Cell Centre conference celebrating its 20 anniversary.
During the last 3 days, we had the chance to share our latest advancements in our research as well as diving into the great research of the center and the amazing invited researchers with international profiles.
Congratulations to everyone who assisted and to the team that made it happen.


WCMM Research day

Today we participated in the 2023 edition of the WCMM research day. All the WCMM researchers came together to share their cutting edge research. In his presentation, Steven shared his progress and accomplishments throughout his Ph.D. and grabbed the price for the best presentation of the day.


Good Bye Yuan

This week was the last one for Yuan in our lab after 2 years working as a bioinformatician across different projects. Now she is continuing her carreer in the National Bioinformatics Infrastructure (NBIS) from Lund.
Best of wishes in your carreer!


Welcome to Aurelie

We welcome Aurelie Baudet to the lab!
In the mini-bones team, she will be focusing on therapy escape in AML, characterizing the response of patient-derived xenografts (conventional and ossicles) to treatment and comparing it to the evolution of the disease in the patient. By tackling the mechanism behind disease relapse, we aim at developing tools predictive of patient’s response to treatment.


Steven presented a recapitulation of his PhD projects in our seminar series.

Today Steven gave a presentation about the new work done on the bioreactor and the mitochondria transfer at the first BMC C12 seminar. Very interactive presentation with plenty of relevant questions. Thanks to Anders Malmström for giving us the opportunity to present our work!


Welcome Patrizia

She has a bachelor's degree in Molecular Medicine from the University of Göttingen in Germany. Since the last two years she has been studying her master’s studies in Molecular Medicine at Uppsala University. Before coming to Lund, she was studying for 6 months at Ghent University, as part of the Erasmus program, to take courses in tissue engineering and regenerative medicine. During her master thesis in our lab, she will investigate the batch-to-batch variation of the MSOD-B cell line and the impact on the quality of 3D-engineered cartilage tissues.


Goodbye Joao

Today Joao finished his internship in our lab. He has been working on characterizing the mitochondrial transfer process between MSCs and HSCs, punching forward the project towards publicaiton.
Best of lucks in the future Joao


Last day of Karin in the lab

Karin has been working with us for the last year working on her master thesis project, studying the effect of RUNX2 CRISPR knock outs as part of her master thesis project.
We are incredibly happy of your pass through the lab and we wish you the best on your future career as a researcher!


We have been awarded a new ERC grant

We have been awarded an ERC P.O.C. grant this will impulse the development of our first spin-off product!


Dimitra presented our Ossicle technology to the Stem Cell Center

During the Stem Cell Center retreat Dimitra took the lead at showing all researchers in the center our model and its many advantages.
Congratulations Dimitra for your fantastic job an effort!


Congratulations Dimitra for your new position

Recently Dimitra starter her new position as a research and product development manager. She will take the lead on the early development of the first group spin-off product.


New Leica Stellaris platform

We recently got installed a new Leica Stellaris confocal microscope, this platform has the advantage of super fast acquisition as well as being capable of live cell imaging. It will soon be available for the Stem Cell Center


Goodbye Ani

Today we say goodbye to Ani, she has been working as a post doctoral researcher in the lab for the last 2 years, working on the characterization of the ossicle model for hematopoiesis.
Now she is moving on in her research career as an independent researcher in Ulm university where she will be researching hematopoiesis and aging.


Congratulations Steven for your succesfull half time defense!

Steven had his PhD thesis halftime, very engaging feedback and special thanks to the reviewing committee composed of Niels-Bjarne Woods, Darcy Wagner, and Jonas Larsson.


Welcome Joao to the team

Welcome to Joao from Lisboa.
Joao Joined the lab as a master student to study the mitochondrial transfer mechanisms occuring between human MSCs and HSCs


Welcome Ludovica to the team

Recently Ludovica joined the team. From the university of Turin she joined to work on the study of iPS-MSCs and their potential to develop bone in in-vivo systems


Congratulations Sujeeth for your successful half time defense

On February 17th Sujeeth defended his half time thesis titled ``Assessing Osteoinductivity and Immunogenicity of Engineered Tissue Grafts``.
Congratulations for your success!


New addition to the team!

Let us introduce David, our latest addition to the team as a PhD student.
His project aims at clearing the mess around the functional diversity of human mesenchymal stem cells (hMSCs) using a combination of tissue engineering and transcriptomix.
Welcome David


New method article from Steven on the engineering of hematopoietic niches in bioreactors!

Steven Dupard describes in this Springer book chapter how 3D hematopoietic niches can be engineered in perfusion bioreactor. This is performed through the differentiation of human mesenchymal cells on specific scaffolding materials.


Congrats Dimitra for receiving a grant from Lund Innovation!

Dimitra Zacharaki received 300,000 SEK through the Exploratory Pre-Seed Programme of Lund Innovation to apply our hOssicle technology in modelling diseases.


New invited review article in press in Experimental Hematology

Congratulations to Paul Bourgine and all coauthors for their invited review article in press in Experimental Hematology!


Congrats Ani for receiving a grant from the Royal Physiographic Society of Lund!

Ani Grigoryan is awarded a 65,000 SEK grant from the Royal Physiographic Society of Lund which will be used to complete a part of her projects in the CTO lab.


Welcome to CTO Nasim!

Nasim Kalantari just joined our lab to conduct a 6-month degree project on the characterization of Ossicle-derived MSOD-B cells as part of her Master’s program on Molecular Medicine at Uppsala University. She has previously worked on human hematopoietic stem cells.


Andrei Chagin visits Lund University

We were honored to have professor Andrei Chagin from Karolinska Institute visit Lund to present his latest work on the epiphyseal stem cell niche. Very stimulating talk and discussion afterwards!


Day treat and retreat to nature for the CTO gang!

We explored the majestic automn palette of Skåne with a hike at Söderåsen national park and ended the day with some fine dining in Lund !


Congrats Paul for being awarded an ERC starting grant!

We are delighted to announce that Paul Bourgine has been awarded a prestigious 5-year ERC starting grant! Everyone at the CTO lab is excited about the upcoming studies on the hOssicle to model hematopoietic disorders.


Goodbye Melissa and Panajot!

This Friday we gathered to say goodbye to Melissa and Panajot who completed their master theses in our lab. Over the past 6 months they learned a lot and contributed to their individual projects with enthusiasm! We thank them and wish them the best of luck with their future plans!


Welcome Tommi!

Tommi Glorioso is a second year-student at the medical programme in Lund. As a summer scholarship project in the CTO lab, Tommi will be involved in the characterization of MSCs capable of cartilage formation in vitro and he will perform quantitative protein assays.


Our humanized ossicle on the cover of Trends in Mol. Med.!

We are very proud and excited to see our first review article published and our humanized ossicle featured on the cover of the current issue of Trends in Molecular Medicine!