Engineered humanized bone organs maintain human hematopoiesis in vivo
Experimental hematology, 2018. Fritsch K, Pigeot S, Bourgine PE, Feng X, Schroeder T, Martin I, Manz MG, Takizawa H Abstract: Hematopoietic stem cells (HSCs) are maintained in a specialized bone marrow (BM) environment, the so-called HSC niche, that provides pivotal factors for their maintenance. Although the cellular and
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